Treatment with synthetic β-lactoglobulin peptides can prevent clinical symptoms in a mouse model for cow’s milk allergy
نویسندگان
چکیده
Background Previous animal studies showed that partial whey hydrolyates could prevent acute allergic symptoms in a mouse model for cow’s milk allergy. This effect was even more pronounced in combination with a diet containing a specific non-digestible oligosaccharide mixture of scGalacto(scGOS), lc-Fructo(lcFOS) and Acidic(pAOS) oligosaccharides (in a 9:1:2 ratio). We hypothesized that these hydrolysates contain peptides that can induce the observed tolerance. Therefore we investigated the potential of synthetic b-lactoglobulin peptides, with or without a diet containing ScGOS/lsFOS/pAOS, to induce tolerance in this mouse model.
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